ASCO Myeloma Information
Medical Supporter — Information Notice
This article is a summary of international medical information and is not medical advice; it cannot replace the diagnosis or treatment plan of your attending physician. The medical technologies, drug information and clinical data presented here are compiled from public literature and official statements of major Japanese medical institutions; the applicability and outcome of any therapy vary with each patient and must be assessed individually by a qualified physician.
Medical Supporter — Information Notice
This article is a summary of international medical information and is not medical advice; it cannot replace the diagnosis or treatment plan of your attending physician. The medical technologies, drug information and clinical data presented here are compiled from public literature and official statements of major Japanese medical institutions; the applicability and outcome of any therapy vary with each patient and must be assessed individually by a qualified physician.
Myeloma Information
- December 11, 2015
- Reading time: 1 minute
This article is a summary translated from ASCO 2015 regarding research on elotuzumab combination therapy for relapsed multiple myeloma. Current Phase III study results show that using elotuzumab and dexamethasone can effectively increase median overall survival by five months. This was presented by Dr. Julie M. Vose, the then President-elect of ASCO.
Elotuzumab is a monoclonal antibody that targets SLAMF7, a protein found on the surface of myeloma cells and on natural killer (NK) cells within the immune system. Elotuzumab directly tags the myeloma cells, which enhances the NK cells' ability to target and destroy them. (Note: Elotuzumab does not increase the number or strength of NK cells but helps them identify and attack the myeloma cells more effectively).
The trial involved 646 participants. For more detailed information, including data and experimental methods, please refer to the following link:
http://meetinglibrary.asco.org/content/144025-156
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