Tokyo Cancer Clinic: 5th Generation Multivalent Dendritic Cell Vaccine (ABeVax) and Photoimmunotherapy
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This article is a summary of international medical information and is not medical advice; it cannot replace the diagnosis or treatment plan of your attending physician. The medical technologies, drug information and clinical data presented here are compiled from public literature and official statements of Japanese medical institutions; the applicability and outcome of any therapy vary with each patient and must be assessed individually by a qualified physician.
Director tokyo
Located in Chiyoda-ku, Tokyo, Tokyo Cancer Clinic is a clinic focused on immunotherapy, led by Dr. Hiroyuki Abe. The clinic has developed its own vaccine preparation method and plans individualized treatment according to each patient's condition.
ABeVax: 5th Generation Dendritic Cell Vaccine
The ABeVax technology developed by Dr. Abe's team is the clinic's method for preparing dendritic cell vaccines:
- Multivalent Design: Unlike single-antigen vaccines, ABeVax is designed to target multiple tumor markers at the same time, with the aim of reducing cases where cancer cells evade immune recognition through antigen changes.
- Small Blood Volume: Vaccines can be prepared from approximately 25ml of blood, which keeps the amount of blood drawn small.
- Cell Culture: The clinic uses its own cell activation method to maintain the antigen-presenting capability of dendritic cells.
Near-Infrared Photoimmunotherapy (PIT)
The clinic also offers Photoimmunotherapy:
- Precision Tagging: Patients are injected with light-sensitive antibody drugs that attach to cancer cells expressing a specific target.
- Light Irradiation: Irradiation with near-infrared light of a specific wavelength damages the cancer cells to which the drug has attached, releasing tumor antigens.
- Combination with the Vaccine: The clinic's approach is to combine the released antigens with the ABeVax vaccine in the hope of inducing an immune response; actual effects vary by individual.
Clinic Information
- Director's Background: Dr. Hiroyuki Abe has long worked in immunotherapy and is committed to building a personalized medical system.
- Access: Located in Kudanshita, near central Tokyo, convenient for planning medical visits.
- Supporting Data: Please ask the clinic about the basis and research data for its treatments during your consultation; this is self-pay care, so please ask the physician about fees and possible risks.
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